BREAD • Biostatistics, Research Ethics And Design Program

Clinical and translational research presents unique methodological, statistical and ethical challenges to investigators. The BREAD Program provides services to help investigators at UCSF and affiliated CTSI institutions meet these challenges successfully and produce research of the highest scientific and ethical standards.

Services:

BREAD services are designed to be easy to access, comprehensive, and integrated, and offer access to experts in the areas of:

• Study Design and Implementation: for questions about study design, sampling, recruitment, measurement, and implementation of both observational studies and clinical trials, including specific support for multicenter clinical trial design and implementation
• Data management: for questions about how to design databases and workflow to support studies, and for assistance with actual programming of a variety of database types, including Web-accessible databases
• Biostatistics: for help with data analysis and interpretation of results, manuscript and grant preparation, statistical aspects of study design, and responding to reviewers.
• Ethics: for complex questions on research ethics, including first-in-human studies, vulnerable populations, stem-cell and gene therapy studies.

Initial consultations are free of charge, with subsequent services provided on a recharge basis. Follow this link for an explanation of our recharge policy.

Submitting a request:

Request a BREAD consultation on-line.

If you have not been contacted by a member of the BREAD consulting team within three business days of submitting your request, call us at 415-502-7893 or email CtsiBread@ucsfmedctr.org.

For more information:
Please send comments or questions to BREAD faculty and staff at:
Email: CtsiBread@ucsfmedctr.org
Phone: 415-502-7893

Who We Are

The BREAD team consists of senior faculty with experience and expertise in many different aspects of clinical and translational research.

Director: S. Claiborne Johnston, MD, PhD
Professor of Neurology and Epidemiology,
Director of the UCSF Stroke Center,
Director of the UCSF Stroke Sciences Group.

Co-Director, Biostatistics: Peter Bacchetti, Ph.D.

Consultants include:

Su-Chun Cheng, DSc, David Glidden, PhD, Barbara Grimes, PhD, Charles E. McCulloch, PhD, Mark R. Segal, PhD.

Co-Director, Data Management: Michael Kohn, MD, MPP

Co-Director, Ethics: Bernard Lo, MD

Consultants include:

Lisa Voss, MPH, Richard Wagner, MA

Co-Director, Research Design: Mark J. Pletcher, MD, MPH

Douglas Bauer, MD, Kirsten Bibbins-Domingo, PhD, MD, Ken Covinsky, MD, Ralph Gonzales, MD, MSPH, Carl Grunfeld, MD, PhD, Thomas Newman, MD, MPH, Rebecca Smith-Bindman, MD, Jeffrey A. Tice, MD, Paul Varosy, MD.