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Frequently Asked Questions


FAQ - Table of Contents


Services and Infrastructure questions

What is the Clinical Research Center (CRC)?

The CRC is a resource that provides a physical location and expertise in research nursing, bionutrition, sample processing, exercise physiology, and DEXA support.

Who can use the CRC?

The CRC is available to UCSF faculty members in the Schools of Medicine, Nursing, Dentistry, and Pharmacy.  In conjunction with research units at the VA Medical Center in San Francisco, Kaiser Division of Research in Oakland, and the, Children’s Hospital Oakland Research Institute, investigators may use the CRC services as well.

What kind of research can be done on the CRC?

The CRC supports human-based translational research. Studies may involve either healthy volunteers or patients with specific diagnoses. ;We facilitate research in a broad area of medical disciplines including general internal medicine, internal medicine subspecialties, radiology, surgery, epidemiology, obstetrics, psychiatry, pediatrics and nursing.

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Policies and scheduling questions

What is the submission deadline for the next SFGH Advisory Committee?

Our submission schedule can be found at http://ctsi.ucsf.edu/crc/schedule.php.

Are non-MDs allowed to conduct studies in the CRC?

Yes.  However all non-MD investigators such as PharmDs and PhDs must have an MD or Nurse Practitioner collaborator who will assume medical responsibility for the research participants.

Can I conduct my research protocol at more than one CRC site?

Yes.  There will be one review by the Advisory Committee.  However, you will need to meet with the staff at each of the sites where you want to conduct your project.

Can projects be submitted to the CRC Advisory Committee prior to CHR approval?

Yes.  The Advisory Committee will accept projects for review prior to or concurrent with the CHR approval process.

How do I get approval for use of the CRC?

A CRC Protocol Utilization Form and CHR Full Committee Application (and approval if already obtained from CHR) are submitted to the CRC Protocol Manager who will coordinate the review by the CRC Advisory Committee for review.  The investigative team works with the Protocol Manager during this process.

Where can I get the CRC application forms?

The application forms are available online at http://ctsi.ucsf.edu/crc/forms.php.

What if I have a project that needs started before the Advisory Committee approval?

If you have CHR approval, you may request administrative approval to start the project prior to full review by the Advisory Committee. This would only be considered if you would miss a rare research opportunity.

What if there are revisions to the original, approved protocol or consent?

All protocol modifications and renewals must be submitted to the CHR and copied to the CRC for review.  If a protocol undergoes major modification, a second presentation to the Advisory Committee may be required. 

How are research participants scheduled?

The research team contacts the CRC Charge Nurse prior to making arrangements with the research participant to insure that space is available. Scheduling depends on the availability of beds, staffing, and equipment.

Who obtains informed consent of the research participant?

It is the responsibility of the principal investigator or appropriate designate to obtain informed consent from the research participant prior to the commencement of a study.

How is medical care provided on the CRC?

The physician investigator is responsible for the medical care of research participants.  Arrangements for emergency care must be formalized before study implementation.

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Budgeting questions

Can I conduct an industry-sponsored project on the CRC?

Yes.  Industry pays for the use of the CRC facilities and staff.  Investigators who need skilled nursing or other support are encouraged to contact the CRC Administrator to inquire about the costs and support available.

What is the pricing for new protocols in CTSI?

Investigators are encouraged to contact the Administrative Director to determine if current CRC resources can cover the cost conducting their research.  However, there is a fee for the conduct of any industry-initiated project.

Do you have funds for ancillary testing?

The CRC does not have funds to cover ancillary testing performed in departments such as the clinical laboratory testing or radiology.

Do I need my own funding to use the CRC? 

Not necessarily.  Although it is ideal to have NIH or other funding, not all research projects have funding.  If a study requires intensive use of resources, Investigators may be asked to share in the cost of such resources that are over and above our basic core level of support.

What happens if the CRC budget is insufficient to cover the costs of all projects utilizing it?

Each project is given a priority score on the basis of scientific merit using the NIH study section scoring system. Should budgetary constraints be placed on the CRC, use of resources will be determined by the priority score.  Investigators may be asked to support the CRC by providing staff and/or funds to offset the cost of the study.

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