Clinical Research Services

Through its Clinical Research Services (CRS) program, CTSI provides a wide array of adult and pediatric services to assist the research community in translating promising clinical research ideas into successful clinical studies. Since 2006, CRS has supported the work of more than 1,500 researchers from UCSF and CTSI affiliates through clinical sites throughout the San Francisco Bay Area.

A CRS effort focusing on Clinical Research Acceleration, one of CTSI’s cross-cutting initiatives, also aims to bring research services directly into community practices to accelerate the pace of clinical and translational research. This includes the implementation of the first-ever UCSF Participant Recruitment Service, a centralized professional resource to facilitate the enrollment of research participants into clinical studies.


Available for researchers, industry collaborators, and study participants:

  • Body Composition and Exercise Physiology Services
  • Nursing Services (Inpatient/Outpatient)
  • NeoNatal Intensive Care Services
  • Sample Processing Services

Providing Critical Support

Through CRS, researchers such as UCSF’s Stephen Deeks, MD, are getting the support they need to translate promising clinical research ideas into successful protocols. 

Dr. Deeks is among a team of leading HIV/AIDS researchers at UCSF working on a major national study designed to investigate the pathogenesis of the HIV disease. At the San Francisco General Hospital (SFGH) site, participants are seen, questionnaires administered, and biologic tissue specimens obtained to help move this research forward.

“Through the outpatient CTSI-supported research unit at SFGH, our group has established and maintained a research infrastructure that allows NIH-supported scientists to translate findings from the laboratory into the clinic and from the clinic back to the laboratory,” Deeks said.

A long-standing working relationship between Dr. Deeks’s team and the CRS not only enables his existing research, but provides resources and services that make it possible for him to secure further funding. With that support he intends to develop a strategy for eradicating HIV from the body.

Changing Practice

In research designed to improve the detection and treatment of a rare condition in infants known as Severe Combined Immunodeficiency (SCID), UCSF researcher Jennifer Puck, MD, utilized CRS services to launch a successful pilot program that has led to changes in how newborns are screened for this deadly disorder.

Among the specialized CRS resources provided to Dr. Puck and her team was the Pediatric Clinical Research Center (PCRC) inpatient isolation room, which supported care of infants affected with SCID who require monitoring of every drop of blood taken for tests.

The study also used the expertise of Rita Jeremy, PhD, a neurodevelopmental psychologist who performed evaluations of children with SCID undergoing bone marrow transplantation. Her assessments included testing the children’s developmental and cognitive functioning, as well as interviewing parents about their perception of their children’s behavior.

“The professionalism combined with warmth and positive attitude of the PCRC staff puts families at ease and helps them cope with difficult situations,” Puck said. “Our patients’ families are anxious—the PCRC is a welcoming place where they get special support.”