Summary of Cross-Cutting Themes and Insights from CTSI Retreat Breakout Groups

These themes and insights are the product of breakout group discussions during the June 14, 2024 CTSI Retreat; participants included over 120 UCSF faculty and staff, and community partners across all UCSF schools and affiliates. 

1. Enhancing Infrastructure and Support:  

  • There is a recurring need for robust support systems, whether in lab processing, decentralized clinical trials (DCTs), or partnerships with Federally Qualified Health Centers (FQHCs). 
  • Proposals include dedicated liaisons, enhanced IT infrastructure, and clear protocols to facilitate effective operation and collaboration.  

2. Communication and Visibility:  

  • Effective communication strategies are crucial across discussions, from increasing lab processing visibility to simplifying language in FQHC partnerships. 
  • Regular updates, success stories, and data-driven narratives are suggested to engage stakeholders and demonstrate the value of various programs and services.  

3. Inclusivity and Community Engagement:  

  • Discussions emphasized the importance of tailoring programs to diverse demographics and ensuring community voices are heard and integrated, particularly in RAP grant review committees and the CIRCLE program.  
  • Strategies include community consultations, building culturally competent and multilingual recruitment cohorts, and leveraging community insights in research and training programs.  

4. Financial Strategies and Resource Allocation:  

  • Financial support is a critical theme, with discussions on securing funding through grants, consistent institutional support, and exploring novel funding models for projects like video production in training modules.  
  • Equitable and flexible funding models are emphasized, particularly for supporting underrepresented communities and ensuring the sustainability of programs.  

5. Technology and Digital Integration:  

  • The role of technology is highlighted in several discussions, from enhancing lab processing services to supporting decentralized clinical trials and AI in healthcare research.  
  • Proposals include leveraging existing digital platforms, integrating new tools like recruitment and tracking tools, and ensuring technology enhances accessibility and engagement without widening existing disparities.  

6. Ethical and Compliance Considerations:  

  • Ethical considerations are paramount, especially in discussions on AI, decentralized clinical trials, and community member inclusion in research review processes. 
  • Ensuring privacy, safety, equitable access, and avoiding exploitation are recurrent themes, with a call for stringent regulatory compliance and ethical governance.  

7. Training and Professional Development:  

  • Continuous professional development and training are crucial, seen in the expansion of the CIRCLE program and the need for training community members in RAP committees. 
  • Emphasizing career pathways, mentorship models, and access to ongoing learning opportunities aligns with the strategic goals of fostering a knowledgeable and adaptive workforce.    

Opportunities and Novel Approaches  

1. Integrating AI and Machine Learning:  

  • Utilizing AI to streamline processes, enhance data analysis, and support decision-making in research settings presents a novel approach to handling large datasets and improving operational efficiency.  

2. Hybrid Models for Training and Development:  

  • Combining one-on-one and group mentorship or in-person and online training modules to expand reach and maintain the quality of personalized coaching and support.  

3. Decentralized and Remote Research Operations:  

  • Developing frameworks for decentralized clinical trials that can increase participant diversity and access, leveraging community health centers, and using mobile health solutions.  

4. Community-driven Research Initiatives:  

  • Structuring research and grant review processes to include community members meaningfully, ensuring research relevance, and enhancing societal impact.  

5. Cross-Institutional and Interdisciplinary Collaborations:  

  • Building partnerships across different institutions and disciplines to pool resources, share knowledge, and tackle complex research challenges more effectively.  

These insights and approaches can be foundational in developing ideas for a grant application, aiming to enhance research capabilities, ensure inclusivity, leverage technology, and maintain ethical standards in innovative ways.