Cancer Exports Molecular ‘Saboteurs’ to Remotely Disarm Immune System

Note: Robert Blelloch, MD, PhD, professor of urology received a Catalyst award in Spring 2018 for the development of small molecule inhibitors of immune checkpoint protein presentation. This included an award and consultation - the Catalyst program team is excited to see the project's progress.

Catalyst Awardee Dena Dubal's Research on Drug to Turbocharge the Brain

Note: The New York Times has published an article featuring the research of Catalyst Awardee and UCSF Professor Dena Dubal, MD, PhD. Dr. Dubal's research investigates the hormone Klotho in potential treatments for dementia and other aging disorders. Dr. Dubal's Fall 2016 Catalyst Award titled, "Brain Resilience: A New Approach for Treating Neurodegenerative Diseases" supported this research through funding and consultations.

One Day There May Be a Drug to Turbocharge the Brain. Who Should Get It?

‘Undruggable’ Parkinson’s Molecule Spills Its Secrets

Note: CTSI's Catalyst Awards program supported this research by Pamela England during her participation in the Spring 2014 cycle.

Successful Pharmacological Activation of Nurr1 Opens Doors to Novel Therapies for Incurable Movement Disorder

By Nicholas Weiler via

How to Patent an Antibody

Note: Charles Craik, PhD, three-time Catalyst Program awardee (Spring 2018, Fall 2016, Spring 2012) shares his insights on intellectual property with the American Society for Biochemistry and Molecular Biology.

By Laurel Oldach via ASBMB Today

Charles Craik knows a lot about patenting research findings.

Catalyst Awardees Apply CRISPR-mediated Activation to Obesity

Researchers Nadav and Navneet
Left to right: Nadav Ahituv, PhD, professor of Bioengineering and Navneet Mattharu, PhD, assistant researcher  

Note: Many diseases are caused by haploinsufficiency, where one of the two copies of the gene is non functional. In this Science publication, the authors used CRISPRa (CRISPR based activa

Catalyst Program Awardee Executes World’s First In Utero Blood Stem Cell Therapy Clinical trial

Tippi MacKenzie (left), MD, of UCSF Benioff Children’s Hospital San Francisco, visits with newborn Elianna, who received a stem cell transplant before birth
Tippi MacKenzie (left), MD, of UCSF Benioff Children’s Hospital San Francisco, visits with newborn Elianna, who received a stem cell transplant before birth. Photo by Barbara Ries

Accelerating Innovations: Catalyst Program Spurs UCSF Scientists and Physicians to Innovate to Help Patients

Surgeons, radiologists, oncologists and others presented their innovative solutions to problems they've encountered in their practices.

Converting Ideas to Products: Catalyst Pairs UCSF Scientists with Business to Improve Clinical Outcome for Patients

By Dan Fost

It’s great to have success, whether in science or in business, but sometimes failure is even better.

UC Launches Drug Discovery Consortium

Catherine Tralau-Stewart, UCSF

Note: The consortium brings together UC's five medical center campuses — Davis, Irvine, Los Angeles, San Diego and San Francisco — to share resources and expertise to help develop new drugs.

By Alec Rosenberg via UC Newsroom

To Get From Bench to Bedside, UCSF Scientists Get Help From Catalyst Program

By Dan Fost

To develop a new drug, or create a new diagnostic test or medical device, a scientist often needs a catalyst – something to spark the innovative idea that has the potential to change the way a disease is treated and improve patient outcomes.