Catalyst

UC Students Gain New Resources, Opportunities Through Expanded Entrepreneurship Program

Note: The Blackstone LaunchPad hub at UCSF will be administered by CTSI's Catalyst Program.

Superfast Gene Sequencing Helps Diagnose Critically Ill Patients

Note: Charles Chiu, MD, PhD, senior author, is a 2014 UC CAI NHLBI Award recipient. The UC CAI program at UCSF is administered and project managed through CTSI's Catalyst program. His project that received UC CAI funding was a rapid unbiased assay for detection of pneumonia - this technique of unbiased next generation sequencing has been used for his other research mentioned in the article.

Tmunity and UCSF Announce Exclusive License and Research Collaboration to Advance TCR T Cell Therapies for Pediatric Cancers

Note: Hideho Okada, MD, PhD, was a Fall 2015 Catalyst Awardee. His project, "Novel Mutation-derived Neoantigen for T Cell Therapy in Gliomas" is now being out-licensed to the immuno-oncology company, Tmunity.

Cancer Exports Molecular ‘Saboteurs’ to Remotely Disarm Immune System

Note: Robert Blelloch, MD, PhD, professor of urology received a Catalyst award in Spring 2018 for the development of small molecule inhibitors of immune checkpoint protein presentation. This included an award and consultation - the Catalyst program team is excited to see the project's progress.

Catalyst Awardee Dena Dubal's Research on Drug to Turbocharge the Brain

Note: The New York Times has published an article featuring the research of Catalyst Awardee and UCSF Professor Dena Dubal, MD, PhD. Dr. Dubal's research investigates the hormone Klotho in potential treatments for dementia and other aging disorders. Dr. Dubal's Fall 2016 Catalyst Award titled, "Brain Resilience: A New Approach for Treating Neurodegenerative Diseases" supported this research through funding and consultations.

One Day There May Be a Drug to Turbocharge the Brain. Who Should Get It?

‘Undruggable’ Parkinson’s Molecule Spills Its Secrets

Note: CTSI's Catalyst Awards program supported this research by Pamela England during her participation in the Spring 2014 cycle.

Successful Pharmacological Activation of Nurr1 Opens Doors to Novel Therapies for Incurable Movement Disorder

By Nicholas Weiler via UCSF.edu

How to Patent an Antibody

Note: Charles Craik, PhD, three-time Catalyst Program awardee (Spring 2018, Fall 2016, Spring 2012) shares his insights on intellectual property with the American Society for Biochemistry and Molecular Biology.

By Laurel Oldach via ASBMB Today

Charles Craik knows a lot about patenting research findings.

Catalyst Awardees Apply CRISPR-mediated Activation to Obesity

Researchers Nadav and Navneet
Left to right: Nadav Ahituv, PhD, professor of Bioengineering and Navneet Mattharu, PhD, assistant researcher  

Note: Many diseases are caused by haploinsufficiency, where one of the two copies of the gene is non functional. In this Science publication, the authors used CRISPRa (CRISPR based activ

Catalyst Program Awardee Executes World’s First In Utero Blood Stem Cell Therapy Clinical trial

Tippi MacKenzie (left), MD, of UCSF Benioff Children’s Hospital San Francisco, visits with newborn Elianna, who received a stem cell transplant before birth
Tippi MacKenzie (left), MD, of UCSF Benioff Children’s Hospital San Francisco, visits with newborn Elianna, who received a stem cell transplant before birth. Photo by Barbara Ries

Accelerating Innovations: Catalyst Program Spurs UCSF Scientists and Physicians to Innovate to Help Patients

Surgeons, radiologists, oncologists and others presented their innovative solutions to problems they've encountered in their practices.

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